COMUNICAÇÃO. Hidradenite supurativa tratada com infliximabe. Daniel Lago ObadiaI; Egon Luiz Rodrigues DaxbacherII; Thiago JeunonIII; Alexandre Carlos. A hidradenite supurativa é uma doença inflamatória da pele que provoca lesões profundas, dolorosas em áreas tais como as axilas e virilhas. Estima-se que. Tratamento cirúrgico de hidradenite axilar supurativa com o uso do retalho paraescapular. Surgical treatment of axillary hidradenitis suppurativa using a.

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Hidradenitis suppurativa HSalso known as acne inversais a long term skin disease characterized by the occurrence of inflamed and swollen lumps. The exact cause is usually unclear but believed to involve a combination of hidgosadenite and environmental factors. There is no known cure. The cause of HS remains unknown and experts disagree over proposed causes. Lesions occur in any body areas with hair follicles, although areas such as the axilla, groin, and perianal region are more commonly involved.

This theory includes most of the following potential indicators: The historical understanding of the disease suggests dysfunctional apocrine glands [9] or dysfunctional hair follicles[10] possibly triggered by a blocked gland, create inflammationpainand a swollen lesion.

Hidradenitis suppurativa treated with infliximab

Several triggering factors should be taken into consideration:. This complex cuts apart cleaves many different proteins, which bidrosadenite an important step in several chemical signaling pathways. One of these pathways, known as Notch signalingis essential for the normal maturation and division of hair follicle cells and other types of skin cells.

Notch signaling is also involved in normal immune system supurayiva. Although little is known about the mechanism, abnormal Notch signaling appears to promote the development of nodules and lead to inflammation in the skin. HS presents itself in three stages.

Hurley separated patients into three groups based largely on the presence and extent of cicatrization and sinuses.

It has been used as a basis for clinical trials in the past and is a useful basis to approach therapy for patients. These three stages are based on Hurley’s staging system, which is simple and relies on the subjective extent of the diseased tissue the patient has. Hurley’s three stages of hidradenitis suppurativa are: The Sartorius staging system is more sophisticated than Hurley’s.

This classification allows for better dynamic monitoring of the disease severity in individual patients. The elements of this staging system are: Points are accumulated in each of the above categories, and added to give both a regional and total score.

In addition, the authors recommend adding a visual analog scale for pain or using the dermatology life hidrosadenitw index DLQI, or the Skindex when assessing HS. Treatment depends upon presentation and severity hidrosadenote the disease. Due to the poorly studied nature of the disease, the effectiveness of the drugs and therapies listed below is unclear.


Warm baths may be tried in those with mild disease. When the process becomes chronic, wide surgical excision is the procedure of choice.

Wounds in the affected area do not heal by secondary intentionand immediate or delayed application of a split-thickness skin graft is an option. With this technique the mostly totally excised defect is covered with living tissue ‘stolen’ from the area nearby.

The nanometer wavelength laser for hair removal may aid in the treatment of HS. In stage III disease, fistulae left undiscovered, undiagnosed, or untreated, can lead to the development of squamous cell carcinomaa rare cancerin the anus or other affected areas. Stage III complications have been known to lead to sepsisbut clinical data is still uncertain.

A surgeon from Paris, Velpeau described an unusual inflammatory process with formation of superficial axillarysub mammaryand perianal abscesses, in a series of three publications from to This hidrosadnite for the disease reflects the former pathogenetic model of acne inversa, which is considered inflammation of sweat glands as the primary cause of hidradenitis suppurativa. InSchiefferdecker suspected a pathogenic association between acne inversa and apocrine sweat glands.

In Pillsbury postulated hidrosqdenite occlusion as the cause of acne inversa, which they grouped together with acne conglobata and perifolliculitis capitis abscendens et suffodiens dissecting cellulitis of the scalp as the “acne triad”.

Hidradenitis suppurativa

Plewig and Kligman added another element to their acne triad, pilonidal sinus. HidrosadenitdPlewig and Supuratvia introduced the term “acne inversa”, indicating a follicular source of the disease and replacing older terms such as “Verneuil disease”.

Hidradenitis suppurativa has been referred to by multiple names in the literature, as well hidroswdenite in various cultures. Some of these are also used to describe different diseases, or specific instances of this disease. Although hidradenitis suppurativa is often referred to as acne inversait is not a form of hidrosadenitr and lacks the core defining features of acne such as the presence of closed comedones and increased sebum production.

From Wikipedia, the free encyclopedia. Archived from the original on 19 February Retrieved 26 October Jemec January 12, N Engl J Med. Archived from the original on 5 September Retrieved 27 October Archived from the original on 28 July Archived from the original on 28 October National Library of Medicine.

Archived from the original on 16 September Retrieved 19 September Archived from the original on 10 September Archived from the original on 6 July Retrieved hdrosadenite July Br J Plast Surg. Body weight in hidradenitis suppurativa. Marks R, Plewig G, editors. Acne and Related disorders. J Am Acad Dermatol.

Retrieved 5 September What is Hidradenitis Suppurativa? Archived from the original on 17 June Axillary hyperhidrosis, apocrine bromhidrosis, hidradenitis suppurativa, and familial benign pemphigus: Marcel Dekker, New York,pp. Journal of the American Academy of Dermatology. The British Journal of Dermatology. A practical review of possible medical treatments based on supurafiva hidradenitis patients”.

Updated Summary of an Original Cochrane Review”. J Clin Aesthet Dermatol. Archived from the original on 6 March Retrieved 4 March Ann Chir Plast Esthet in French. Complications resulting in death”. Archives of General Medicine in French. In Marks R, Plewig G.


Acne and Related Disorders. An appeal to finally abandon a misnomer”. International Journal of Dermatology. Arch Gen Med in French. A clinicopathological study of early lesions”. Disorders of skin appendages L60—L75— Beau’s lines Yellow nail syndrome Leukonychia Azure lunula shape: Koilonychia Nail clubbing behavior: Ingrown hidrosadeniye Anonychia ungrouped: Paronychia Acute Chronic Chevron nail Congenital onychodysplasia of the index fingers Green nails Half and half nails Hangnail Hapalonychia Hook nail Ingrown nail Lichen planus of the nails Longitudinal erythronychia Malalignment of the nail plate Median nail dystrophy Mees’ lines Melanonychia Muehrcke’s lines Nail—patella syndrome Onychoatrophy Onycholysis Onychomadesis Onychomatricoma Onychomycosis Onychophosis Onychoptosis defluvium Onychorrhexis Onychoschizia Platonychia Pincer nails Plummer’s nail Psoriatic nails Pterygium inversum unguis Pterygium unguis Purpura of the nail bed Racquet nail Red lunulae Shell nail syndrome Splinter hemorrhage Spotted lunulae Staining of the nail plate Stippled nails Subungual hematoma Terry’s nails Twenty-nail dystrophy.

Alopecia areata totalis universalis Ophiasis Hidrodadenite alopecia male-pattern baldness Hypotrichosis Telogen effluvium Traction alopecia Lichen planopilaris Trichorrhexis nodosa Alopecia neoplastica Anagen effluvium Alopecia mucinosa cicatricial alopecia: Pseudopelade of Brocq Central centrifugal cicatricial alopecia Pressure alopecia Traumatic alopecia Tumor alopecia Hot comb alopecia Perifolliculitis capitis abscedens et suffodiens Graham-Little syndrome Folliculitis decalvans ungrouped: Triangular alopecia Frontal fibrosing alopecia Marie Unna hereditary hypotrichosis.

Hirsutism Acquired localised generalised patterned Congenital generalised localised X-linked Prepubertal. Perioral dermatitis Granulomatous perioral dermatitis Phymatous rosacea Rhinophyma Blepharophyma Gnathophyma Metophyma Otophyma Papulopustular rosacea Lupoid rosacea Erythrotelangiectatic rosacea Glandular rosacea Gram-negative rosacea Steroid rosacea Ocular rosacea Persistent edema of rosacea Rosacea supurativva variants Periorificial dermatitis Pyoderma faciale.

Hidradenite supurativa – Sintomas, Tratamentos e Causas | Minha Vida |

Folliculitis Folliculitis nares perforans Tufted folliculitis Pseudofolliculitis barbae Hidradenitis Hidradenitis suppurativa Recurrent palmoplantar hidradenitis Neutrophilic eccrine hidradenitis. Acrokeratosis paraneoplastica of Bazex Acroosteolysis Bubble hair deformity Disseminate and recurrent infundibulofolliculitis Erosive pustular dermatitis of the scalp Erythromelanosis follicularis faciei et colli Hair casts Hair follicle nevus Intermittent hair—follicle dystrophy Keratosis pilaris atropicans Kinking hair Koenen’s tumor Lichen planopilaris Lichen spinulosus Loose hidrosadenitte syndrome Menkes kinky hair syndrome Monilethrix Parakeratosis pustulosa Pili Pili annulati Pili bifurcati Pili multigemini Pili pseudoannulati Pili torti Pityriasis amiantacea Plica neuropathica Poliosis Rubinstein—Taybi syndrome Setleis syndrome Traumatic anserine folliculosis Trichomegaly Trichomycosis axillaris Trichorrhexis Trichorrhexis invaginata Trichorrhexis nodosa Trichostasis spinulosa Uncombable hair syndrome Wooly hair Wooly hair nevus.

Body odor Chromhidrosis Fox—Fordyce disease. Retrieved from ” https: Acneiform eruptions Inflammations Rare diseases. Views Read Edit View history. In other projects Wikimedia Commons. This page was last edited on 15 Novemberat